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In vitro and in vivo evaluation of high-dose inhaled rifampicin powder formulations for tuberculosis treatment
Conference presentation   Open access

In vitro and in vivo evaluation of high-dose inhaled rifampicin powder formulations for tuberculosis treatment

P. Khadka, S. Sinha, P.C. Hill, J. Dummer, I.G. Tucker, R.G. Katare and S.C. Das
Otago Medical School Research Society Meeting - PhD Student Speaker Awards, 259th (Dunedin, New Zealand)
OMSRS - PhD Student Speaker Awards, New Zealand Medical Association
17/12/2021
Handle:
https://hdl.handle.net/10523/12943
Appears in  Otago Medical School Research Society

Abstract

tuberculosis drug delivery treatment pulmonary drug delivery anti-TB inhalable rifampicin
Despite the availability of oral and injectable drugs, tuberculosis (TB) treatment is hindered by suboptimal drug concentrations in the lungs and blood. Pulmonary delivery of anti-TB drugs may ensure sufficient drug concentration in the lungs and blood. This study reports on the in vitro and in vivo (rat) assessments of inhalable rifampicin formulations.
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