Abstract
Alzheimer's Disease (AD), the most common form of dementia, is a significant and growing health challenge worldwide. Current available treatments for AD have poor efficacy. Decreased activity within default-mode network (DMN) has been demonstrated as a potential biomarker for tracking AD progression and is a recommended target for brain stimulation.
This pilot study explored a novel high-definition transcranial infra-slow pink noise stimulation (HD-tIPNS) technique for increasing DMN activity in individuals with early AD.